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Fig. 1 | Journal of Experimental & Clinical Cancer Research

Fig. 1

From: The immune microenvironment of HPV-positive and HPV-negative oropharyngeal squamous cell carcinoma: a multiparametric quantitative and spatial analysis unveils a rationale to target treatment-naïve tumors with immune checkpoint inhibitors

Fig. 1

Differential expression of immune-related genes in HPV-positive and HPV-negative OPSCC. (A) Volcano plot depicting significantly increased (right) or decreased (left) expression of immune-related genes in HPV-positive OPSCC. (B) Differential expression of predefined pathway genes and (C) gene expression-based cell types in HPV-positive and HPV-negative OPSCC. Significantly different data are represented by *p < 0.05, **p < 0.01, ***p < 0.001 and ****p < 0.0001

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