Fig. 5

Preparation and characterization of DOX/sh-1@PLT. A and C Particle size analysis and zeta potential analysis technologies were used to detect sh-1, DOX, PLTs, and DOX/sh-1@PLTs. B Detection of PLT and DOX/sh-1@PLT by SEM. D Detection of the stability of DOX/sh-1@PLT by UV spectrophotometry. E–F Characterization of DOX/sh-1@PLT by laser confocal microscopy (E) and western blot assay (F). G Detection of the excitation process of DOX/sh-1@PLT by SEM. H Detection of the release rate of DOX/sh-1@PLT by UV spectrophotometry. I-J Detection of the ability of DOX/sh-1@PLT to target HCC cells by transwell chamber assay (I) and the 3D tumor ball assay (J)