Table 3 Selected list of clinical trials exploring ncRNAs as cancer biomarkers
Name | ncRNA Class | Cancer Type | Source | Implications | Trial Identifier | Trail Status |
|---|---|---|---|---|---|---|
let-7 | miRNA | Non-Hodgkin’s Lymphoma and Acute Leukemia | Tissue | Diagnostic | Recruiting | |
miR-10b | miRNA | Glioma | Tissue, Blood and Cerebrospinal Fluid | Prognostic for OS and PFS | Recruiting | |
miR-30 | miRNA | Prostate Cancer | Blood | Diagnostic and Prognostic | Recruiting | |
miR-31-3p | miRNA | Colorectal Cancer | tissue | Prognostic for DFS, OS and SAR | Completed | |
miR-34a | miRNA | Acute Myeloid Leukemia | Tissue | Diagnostic | Completed | |
miR-141 | miRNA | Prostate Cancer | Tissue | Prognostic for PFS | Recruiting | |
Unknown | ||||||
miR-200(a, b, c) | miRNA | Ovarian Cancer | Blood | Prognostic for PFS | Recruiting | |
Unknown | ||||||
miR-200b | miRNA | Ovarian, and Colon Cancer (Stage IV) | Blood | Prognostic for PFS | Recruiting | |
Predictive and Prognostic. | Recruiting | |||||
miR-203 | miRNA | Colon Cancer (Stage IV) | Blood | Predictive and Prognostic. | Recruiting | |
miR-374a | miRNA | Prostate Cancer | Blood | Prognostic for PFS | Recruiting | |
miR-375 | miRNA | Prostate Cancer, Merkel Carcinoma | Tissue, Blood | Diagnostic | Unknown | |
Unknown | ||||||
CCAT1 | lncRNA | Colorectal Cancer | Blood | Diagnostic | Unknown | |
H19 | lncRNA | Liver Cancer | Blood | Diagnostic | Completed | |
HOTAIR | lncRNA | Thyroid Cancer | Blood | Diagnostic | Unknown | |
PVT1 | lncRNA | Gastrointestinal Cancer | Blood | Diagnostic | Unknown | |
UCA-1 | lncRNA | Liver Cancer | Tissue | Diagnostic | Recruiting | |
XIST | lncRNA | Acute Myeloid Leukemia | Tissue, Blood | Diagnostic | Not Yet Recruiting |