Fig. 2
From: Flavokawain A is a natural inhibitor of PRMT5 in bladder cancer
PRMT5 expression correlated with poor prognosis in BC tissues and cell lines. a Gene ontology analysis for the biological process of differentially expressed genes based on PRMT5 expression in three BC datasets. b KEGG annotation of differentially expressed genes based on PRMT5 expression in three BC datasets. c Kaplan–Meier analysis of survival prognosis based on PRMT5 expression in GEO datasets. d qPCR analysis of PRMT5 expression in BC tissues and adjacent normal bladder tissues. e Kaplan–Meier analysis of survival based on PRMT5 expression in patients. f Western blot analysis of PRMT5 expression and histone methylation level in BC tissues and adjacent normal bladder tissues. g Cell viability analysis of different BC cell lines by knocking down PRMT5 or treatment with gemcitabine and cisplatin