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Table 2 Patient Characteristics

From: Phase 2 study of AV-GBM-1 (a tumor-initiating cell targeted dendritic cell vaccine) in newly diagnosed Glioblastoma patients: safety and efficacy assessment

Variable

N = 60 (100%)

Age

 Median

59 years

 Range

29 to 70 years

Gender

 Male

42 (70%)

 Female

18 (30%

Race/Ethnicity

 Asian

1 (1.7%)

 Black

2 (3.3%)

 Hispanic

10 (17%)

 Other

3 (5.0%)

 White

43 (72%)

KPS at baseline

 70

14 (23%)

 80

17 (28%)

 90

25 (42%)

 100

4 (7%)

MGMT promoter status

 Methylated

20 (33%)

 Unmethylated

39 (65%)

 Equivocal

1 (2%)

IDH1/2 genes

 Mutated

7 (12%)

 Not Mutated

53 (88%)

Anatomic Location of Tumor

 Frontal

Left 11 (18%), Right 5 (8.3%)

 Parietal

Left 6 (10%), Right 8 (13%)

 Temporal

Left 7 (12%), Right 13 (22%)

 Occipital

Left 2 (3.3%), Right 1 (1.7%)

 Fronto-Temporal

Left 0 (0%), Right 1 (1.7%)

 Parieto-Occipital

Left 1 (1.7%) Right 0 (0%)

 Temporo-Occipital

Left 0 (0%) Right 1 (1.7%)

 Temporo-parieto-occipital

Left 1 (1.7%), Right 0 (0%)

 Temporal and Amygdala

Left 0 (0%), Right 1 (1.7%)

 Insula

Left 1 (1.7%), Right 0 (0%)

 Corpus callosum

Left 1 (1.7%), Right 0 (0%)