Fig. 1

 A virtual screening strategy identified c-Jun inhibitors. A Schematic representation of the virtual screening strategy. B An Upset plot of ADMET property analysis for the hits. C Molecular structure of AIL. D Potential targets of AIL predicted by our proposed strategy. E Accuracy scores of consensus QSAR models and single SAR models based on three descriptors. F AUC scores of consensus QSAR models and single SAR models based on three descriptors. G The optimal structural conformation of c-Jun and the ligand AIL