Fig. 1

Downregulation of KLF14 is correlated with poor prognosis in HCC. A Relative mRNA level of KLF14 in 69 paired tumor tissues and adjacent tissues of HCC. B Expression ratios of “tumor tissues/adjacent tissues” in HCC were calculated and shown as histogram (n = 69). C The protein level of KLF14 in tumor tissues and its matched adjacent tissues. D The protein level of KLF14 in normal liver cells and HCC cell lines. E Representative Immunohistochemistry staining of KLF14 in HCC tumor and adjacent tissues (n = 90) were exhibited (scale bar, 100 μm). F Alteration of KLF14 expression in paired samples are depicted in the pie chart. G-H Kaplan-Meier analyses were conducted to evaluate the overall survival (G) and disease-free survival (H) according to the expression of KLF14 in HCC tissue chip (n = 90). Data are presented as the mean ± SD. Two-tailed unpaired Student’s T-tests were performed. ***P < 0.001