Fig. 6
A Subcellular localization of HIF1α in Huh7SR and 7721SR cells overexpressing FASN under both normoxic and hypoxic conditions. B Subcellular localization of HIF1α in Huh7SR and 7721SR cells depleted of FASN under both normoxic and hypoxic conditions. C Nuclear and cytoplasmic expression of HIF1α in Huh7SR and 7721SR cells overexpressing FASN under normoxic and hypoxic conditions. D The half-life of HIF1α protein in Huh7SR cells with knockdown and overexpression of FASN. E The ubiquitination of HIF1α protein in FASN-knockdown Huh7SR and 7721SR cells. F The ubiquitination of HIF1α protein in Huh7SR and 7721SR cells overexpressing FASN