Fig. 2

Changes in METTL3 expression were found in breast cancer tissues. a The protein level of METTL3 in breast cancer tissues and adjacent normal tissues, n = 8. b The expression of METTL3 protein in breast cancer tissues and normal tissues by IHC in the TMA (129 breast cancer tissue samples and 3 normal breast tissue samples). Strong staining of mettl3 was detected in breast cancer tissues (upper panel) and weak staining was detected in normal tissues (lower panel). c High METTL3 protein expression was significantly associated with poor prognosis of invasive ductal carcinoma, p < 0.05. d The protein level of METTL3 in 6 different breast cancer cell lines