Fig. 1
From: TRIM21 attenuates renal carcinoma lipogenesis and malignancy by regulating SREBF1 protein stability
TRIM21 silencing attenuates the dependence of RCC cells on fatty acids. A and B Western blot was used to detect the efficiency of TRIM21 knockdown in ACHN and 786-O, and GAPDH was used as a loading control. C-H Oxygen consumption rate (OCAR) was analyzed when TRIM21 was knockdown in ACHN and 786-O by Seahorse analysis. I-J The maximum respiratory capacity was analyzed when TRIM21 was knockdown in ACHN and 786-O. All the results were confirmed by three times repeated experiments. Statistical analysis was performed using unpaired t-tests. All statistical tests were two-sided. *p < 0.05, **p < 0.01, ***p < 0.001