Table 2 Significant up- and down-regulation gene expressions between LM and LMA2. LM represented twice LPPC/MP treatments in mice, and LMA2 indicated that twice LPPC/MP/CD28 treatments after LM treatment in mice

Upregulation

Prss34

4.557

6.883

0.002

Ms4a3

4.002

6.635

0.005

Nlrx1

2.279

2.582

0.006

Mmp8

5.011

8.476

0.010

Prtn3

16.725

21.497

0.011

Cd177

10.162

16.802

0.012

Apbb1ip

74.910

80.799

0.013

Chil1

3.392

5.876

0.015

Itgam

93.079

101.966

0.015

Fcnb

5.854

10.087

0.017

Mr1

7.138

8.195

0.018

Gm49368

70.053

76.326

0.020

Irf7

58.187

72.475

0.020

Anxa1

176.462

209.383

0.021

AA467197

1.565

3.047

0.023

Elane

16.589

23.015

0.023

Ltf

61.203

99.328

0.023

Trem3

7.609

10.223

0.024

Arg1

0.506

0.772

0.026

Ptges

1.389

1.681

0.027

Il6

0.572

1.231

0.027

Cebpb

21.577

23.400

0.030

Septin5

1.912

2.529

0.030

Ctsg

8.174

14.154

0.030

Acod1

32.192

35.813

0.033

Cxcl2

14.433

18.646

0.033

Il18

15.711

14.539

0.034

Gab2

15.537

16.640

0.038

Pik3ap1

83.432

87.592

0.040

Cd300e

13.494

14.705

0.042

Trem1

4.465

7.618

0.047

Mapk13

0.940

2.014

0.048

Olfm4

3.476

5.904

0.048

Cd44

79.985

84.837

0.049

Downregulation

N4bp1

5.237

5.447

0.006

Erap1

14.454

15.325

0.018

Det1

2.791

2.309

0.037

Btbd3

0.362

0.246

0.048

Smurf2

7.593

6.616

0.049