Fig. 8

Pro pretreatment prevents metastasis of PCa cells in vivo. A and B Representative images of mice pretreated with PBS or Pro (1 mg/kg/day for 3 days) followed by C4-2B (n=5) (A) or PC-3 (n=6) (B) injection through left ventricle. Pictures were taken 3 weeks after inoculation. Number of metastases was counted on the right. C and D Mice used in the previous step were treated with PBS or Pro (2 mg/kg). Survival rate of mice bearing C4-2B (C) and PC-3 (D) was calculated. **P < 0.01, ***P < 0.001