Exosomal cargos-mediated metabolic reprogramming in tumor microenvironment

Table 1 Major subtypes of EVs and their physiological characteristics

EVs subtype	Characteristics				Reference
EVs subtype	Size (nm in diameter)	Membrane	Origin	Markers	Reference
Exosomes	40–160	Double	ILVs	CD9, CD63, CD81, HSP70, TSG101, flotillin-1, ALIX	[12]
Microvesicles	100–1000	Double	Plasma membrane	Selectins, intergrins, CD40, ARF6	[6]
Apoptotic bodies	50–5000	Double	Plasma membrane (during apoptosis)	C1q, ICAM-3, clathrin, Calreticulin, CD44v6	[5]
Exomeres	< 50	Non	Separation from exosomes	Hsp90-b,	[7]
Supermeres	Around half the volume of exomere	Non	Separation from exomeres	TGFBi	[8]
Migrasomes	500–3000	Double	Retraction fibres (during migration)	NDST1, PIGK, CPQ, EOGT	[10]
Mitosomes		Double	Separation from migrasomes		[11]

ISSN: 1756-9966