Table 4 miRNA cancer therapeutics in clinal trials
From: Research progress on non-protein-targeted drugs for cancer therapy
Target | Drug name | Cancer | ClinicalTrials. gov Identifier | Current status |
|---|---|---|---|---|
miR-16 | TargomiRs | MPM, NSCLC | NCT02369198 | Phase I completed |
miR-34a | MRX34 | Primary liver cancer, solid tumors, hematologic malignancies | NCT01829971 | Phase I terminated (Five immune related serious adverse events) |
miR-155 | Cobomarsen | Lymphoma, leukemia | NCT02580552 | Phase I completed |
miR-29 | Remlarsen | Keloid | NCT03601052 | Phase II completed |