CLDN6 inhibits breast cancer metastasis through WIP-dependent actin cytoskeleton-mediated autophagy

Table 1 The association between CLDN6, WIP and LC3 expression and clinical characteristics of breast cancer patients

Clinicopathologic	CLDN6		P	WIP		P	LC3		P
Features	Low	High	P	Low	High	P	Low	High	P
Age			0.8146			0.511			0.1763
≤ 57 years	21	5		21	5		20	6
> 57 years	26	4		22	8		18	12
Tumor size			0.7645			0.1839			0.5923
≤ 3 cm	30	6		25	11		24	12
> 3 cm	16	3		17	2		14	5
Pathology grade			0.1881			0.8305			0.5447
I—II	20	6		20	6		19	7
II—III	27	2		23	6		19	10
Lymph node			0.7808			0.0192*			0.3666
Negative	22	4		16	10		17	9
Positive	17	5		20	2		17	5
TNM stage			0.294			0.2963			0.3305
0—II	35	5		29	11		26	14
III—IV	13	5		16	2		14	4

ISSN: 1756-9966