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Table 1 Association of membrane EGFR localization with the clinical prognostic characteristics of the OC cohort

From: Biological and clinical impact of membrane EGFR expression in a subgroup of OC patients from the phase IV ovarian cancer MITO-16A/MANGO-OV2A trial

 

EGFR

M0

N (%)

M

N (%)

MM

N (%)

p-value

(N = 152)

(N = 145)

(N = 13)

Age

  < 65

105 (69.1%)

104 (71.7%)

11 (84.6%)

0.522

  >  = 65

47 (30.9%)

41 (28.3%)

2 (15.4%)

 

Stadio (3 vs 4)

 III

119 (78.3%)

120 (82.8%)

11 (84.6%)

0.611

 IV

33 (21.7%)

25 (17.2%)

2 (15.4%)

 

ECOG

 0

120 (78.9%)

117 (80.7%)

11 (84.6%)

0.938

 1–2

32 (21.1%)

28 (19.3%)

2 (15.4%)

 

Tumor histology

 HGSOC

136 (89.5%)

123 (84.8%)

6 (46.2%)

 < 0.001

 Other

16 (10.5%)

22 (15.2%)

7 (53.8%)

 

Residual

 None

66 (43.4%)

58 (40.0%)

7 (53.8%)

0.787

  <  = 1 cm

27 (17.8%)

33 (22.8%)

3 (23.1%)

 

  > 1 cm

49 (32.2%)

45 (31.0%)

2 (15.4%)

 

 No surgery

10 (6.6%)

9 (6.2%)

1 (7.7%)