Fig. 1

FYN is highly expressed in GC and is strongly associated with poor prognosis in GC patients. A The FYN genetic alterations (gene amplification, deep deletion, or somatic mutation) and mRNA expression in GC samples from the TCGA cohort (total alteration rate: 7%). B FYN mRNA expression is upregulated in the tumor tissues compared with it in normal tissue group from TCGA. C FYN mRNA high expression GC has poor overall survival. D FYN mRNA high expression GC has poor progression-free survival. E–F FYN expression was higher in gastric cancer tissues than in paraneoplastic tissues (p < 0.05). G Overexpressed FYN was associated with poor overall survival in GCs (p < 0.05).H. Specificity of ROC curve to detect FYN as a diagnostic marker for GC