Fig. 2

α-SMA⁺ CAFs at the invasive front correlate with clinical outcome of ESCC patients. A Representative images of α-SMA IHC staining in ESCC samples (scale bars, 50 μm). B IHC scores of α-SMA⁺ CAFs at the invasive front and lamina propria are lower than that in the tumor stroma of ESCC. C/D Kaplan–Meier curves indicate that high α-SMA⁺ CAFs at the invasive front of ESCC correlate with shorter OS and DFS in ESCC patients