Epigenetic reprogramming-induced guanidinoacetic acid synthesis promotes pancreatic cancer metastasis and transcription-activating histone modifications

Table 1 Clinicopathological features of 81 postoperative patients with pancreatic cancer

Patients’ characteristics	n	GATM^h (n, %) expression	Pearson χ²	P
Sex			1.035	0.439
Male	43	38(88.4)
Female	38	36(94.7)
Age (years)			0.297	0.586
≤ 60	34	16(47.1)
> 60	47	25(53.2)
Location			0.602	0.438
Head/neck	50	33(66.0)
Body/tail	31	23(74.2)
Differentiation			3.393	0.065
Low	28	5(17.8)
Moderate/High	53	20(37.7)
Primary tumor size			0.392	1.000
T1	13	0(0.0)
T2 + T3	68	2(2.9)
Lymph node metastasis			12.415	0.001
N0	29	21(72.4)
N1 + N2	52	51(98.1)
TNM stage			13.113	0.001
I	22	15(68.2)
II + III	59	57(96.6)

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