Fig. 3

cZNF215 facilitates iCCA progression and metastasis in vivo. A and B Subcutaneous xenografts of the indicated cells dissected from nude mice, and growth curves of tumor volumes were calculated in the subcutaneous xenograft models (n=5). C and E Representative bioluminescent images after inoculation with HuCCT1 and RBE cells, respectively, in liver orthotopic-implantation models (n=5). D and F Representative fluorescent images and hematoxylin-eosin (HE) staining of metastatic nodules in liver orthotopic-implantation models (n=5). G and I Representative bioluminescent images after inoculation with HuCCT1 and RBE cells, respectively, in lung metastasis models (n=5). H and J Representative fluorescent images and HE staining of metastatic nodules in lung metastasis models (n=5)