Fig. 6

Analysis of validating scRNA-seq datasets. A The UMAP plot of subset T cells, colored by T cell clusters. B The UMAP plots of the expression of selected genes as in (A). C The scatter plot of the AUCell expressions of gene signatures of exhausted T cells and tissue-resident memory T cells between T cell clusters, colored by cell clusters. D The dot plot of the expression percentage and intensity of genes in exhausted T cells and tissue-resident memory T cells between C2 and C3 T cell clusters. (E) The volcano plots of differentially expressed genes of C2 + C3 T cells between HBV + and HBV- samples in TB tissues, labeled with typical marker genes. F The GO pathway analyses of shared upregulated genes (left) and downregulated genes (right) between HBV + and HBV- C2 + C3 T cells in TB tissues, the pathway names were labeled