Fig. 7From: Energy stress-induced circZFR enhances oxidative phosphorylation in lung adenocarcinoma via regulating alternative splicingGraphical illustration of mechanism in LUAD progress. The elevated circZFR levels upon glucose stress protect HNRNPLL protein from degradation by ubiquitination, which promotes the inclusion of MYO1B exon 23 to enhance OXPHOS via AKT-mTOR signaling to promote tumor growthBack to article page