Fig. 1
From: AXL in cancer: a modulator of drug resistance and therapeutic target
The structure of AXL and GAS6. A The AXL protein comprises an intracellular domain, single helix transmembrane region, two fibronectin type III (FNIII) domains, and two immunoglobulin (IG)-like domains. On the other hand, GAS6 consists of a γ-carboxyglutamic acid (GLA) domain, a loop region, four epidermal growth factor (EGF)-like repeats, and two globular laminin G like (LG) domains. In Figure B and C, we can observe the interaction between AXL and GAS6, front both the front and top sides respectively, as visualized in the Protein Data Bank (PDB) with the identifier 2C5D