Fig. 3From: Liver metastasis from colorectal cancer: pathogenetic development, immune landscape of the tumour microenvironment and therapeutic approachesThe role of CD8+ T cells in hepatic immune tolerance. To maintain homeostasis in the liver, which is exposed to an increased burden of harmless dietary factors and antigens, effector CD8+ T cells are induced to undergo anergy, differentiation or apoptosisBack to article page