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Fig.5 | Journal of Experimental & Clinical Cancer Research

Fig.5

From: Cellular hierarchy framework based on single-cell/multi-patient sample sequencing reveals metabolic biomarker PYGL as a therapeutic target for HNSCC

Fig.5

Chemotherapy resistance and metastasis of HNSCC promoted by PYGL. A Prediction of cisplatin IC50 in METArisk-high and METArisk-low groups. B Prediction of cisplatin IC50 in high and low PYGL expression groups. C Computational analysis of resistance with PYGL of cisplatin in the CARE database. D Tumor growth was measured once a week in tumor-bearing nude mice stably transfected with HNSCC cells (n = 5). E The tumors were removed, and the tumor weight was analyzed after the mice were executed. F Metastasis of HNSCC was measured by the results of hematoxylin–eosin staining of mice lung tissue

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