Fig. 5

Tumor-associated fibrosis. A, B Hematoxylin and eosin (H&E) staining of human ovarian tumor tissues. Representative tissues from patients with (A) normal BMI (n = 6) or (B) high BMI (n = 7) were stained using H&E. Fibrotic tissue (pink) is more evident in the high BMI cohort. C, D Trichrome staining of tumors from LFD and HFD mice. Tumor sections from mice on (C) LFD (n = 11) or (D) HFD (n = 10) were stained using trichrome reagents according to the manufacturer’s specifications. Representative images are shown. Collagen staining (blue) is more evident in the HFD cohort. Scale bar 200 μm