Fig. 1

Supplementation of B. adolescentis suppressed colorectal tumorigenesis in mice. A Representative colorectum images of AOM/DSS mice treated with B.adolescentis (B.a; n = 5), E. coli (n = 5), or vehicle (PBS) (n = 5). The red arrows indicate the tumor locations. B, C Tumor number and load in the colorectum were measured. D-F Representative images and percentages of Ki67 and CD31 in colorectal cancer tissue by immunostaining; white scale bars, 200 μm; black scale bars, 50 μm. Data are shown as mean ± SD. * P < 0.05, ** P < 0.01, **** P < 0.0001; ANOVA test (B, C, E, F)