Fig.3

Membrane protrusions and motile phenotype in RAGE-overexpressing BC cells. A Scanning electron microscopy (SEM) images of wild type (MCF7/wt) and RAGE-overexpressing (MCF7/RAGE) MCF7 cells; scale bar: 10 μm. B Higher magnification (square in A), scale bar: 3 μm. C SEM images of wild type (T47D/wt) and RAGE-overexpressing (T47D/RAGE) T47D cells; scale bar: 10 μm. D Higher magnification (square in C), scale bar: 2 μm. Transwell migration (E–F) and invasion (G-H) assays in wild type and RAGE-overexpressing MCF7 and T47D cells. Cells were counted in at least 5 random fields in three independent experiments performed in triplicate, as quantified in the side panels. Scale bar 200 μm