Fig. 11From: The new world of RNA diagnostics and therapeuticsModel of the axis Che-1/miR-590-3p/ TAZ that sustains the tumor progression in MM cells. In MM cells Che-1 is upregulated and recruited on the promoter of EIF4H, the host gene of miR-590-3p. The miRNA downregulates TAZ both on transcriptional and post-translational level promoting cell proliferationBack to article page