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Table 1 List of the 22 genes upregulated in colon to liver metastasis compared to primary colon tumor. Data represent the intersection between our original dataset and two publicly available ones, as indicated in the text

From: Interrogating colorectal cancer metastasis to liver: a search for clinically viable compounds and mechanistic insights in colorectal cancer Patient Derived Organoids

Gene

Gene name

Ensembl ID

RNA tissue enrichment

APOB

Apolipoprotein B

ENSG00000084674

intestine: 224.8;liver: 442.2

APOF

Apolipoprotein F

ENSG00000175336

liver: 114.0

ASGR2

Asialoglycoprotein receptor 2

ENSG00000161944

liver: 154.1

C9

Complement C9

ENSG00000113600

liver: 419.5

CPB2

Carboxypeptidase B2

ENSG00000080618

liver: 246.8

CPN2

Carboxypeptidase N subunit 2

ENSG00000178772

liver: 225.5

CRP

C-reactive protein

ENSG00000132693

liver: 1139.7

CYP2E1

Cytochrome P450 family 2 subfamily E member 1

ENSG00000130649

liver: 802.4

DPYS

Dihydropyrimidinase

ENSG00000147647

kidney: 42.2;liver: 103.6

FGA

Fibrinogen alpha chain

ENSG00000171560

liver: 2009.3

FGB

Fibrinogen beta chain

ENSG00000171564

liver: 1908.6

FGG

Fibrinogen gamma chain

ENSG00000171557

liver: 2225.7

FGL1

Fibrinogen like 1

ENSG00000104760

liver: 450.7

GC

GC, vitamin D binding protein

ENSG00000145321

liver: 552.1

HPR

Haptoglobin-related protein

ENSG00000261701

liver: 151.4

ITIH3

Inter-alpha-trypsin inhibitor heavy chain 3

ENSG00000162267

liver: 326.9

ITIH4

Inter-alpha-trypsin inhibitor heavy chain family member 4

ENSG00000055955

liver: 461.4

LBP

Lipopolysaccharide binding protein

ENSG00000129988

liver: 429.7

ORM1

Orosomucoid 1

ENSG00000229314

liver: 834.6

PRG4

Proteoglycan 4

ENSG00000116690

adipose tissue: 20.9;liver: 76.0

VTN

Vitronectin

ENSG00000109072

liver: 321.7

SLC13A5

Solute carrier family 13 member 5

ENSG00000141485

liver: 150.4;salivary gland: 153.9