From: Super-enhancers complexes zoom in transcription in cancer
Classify | methods | Database | Functions of database | Website | Ref |
---|---|---|---|---|---|
Identify SEs | ChIP-Seq, 3C, 4C, 5C, Hi-C | dbSUPER | The first comprehensive, interactive database of SEs involved in cellular identity and disease transcriptional control | [202] | |
SEA | Lncludes SEs from several species and information on how they affect cellular identity | [203] | |||
Study the function of SEs | CRISPR/Cas9 | Cistrome Cancer | A comprehensive resource for predicted "SE" target genes and enhancer profiles and TF targets | [208] | |
SEA version 3.0 | A comprehensive database covering all available SE information for multiple species and will facilitate the study of SE function | [209] | |||
Regulatory mechanisms of SEs | 3C, 4C, 5C, Hi-C, ChIP-seq,ATAC-Seq, CUT&Tag, CRISPR/Cas9 | SE analysis | A database used to analyze the regulatory mechanisms of SEs | [67] | |
SEdb | A database that provides basic information about SEs and can also combine, evaluate, and disclose the regulatory mechanisms of SEs | [210] | |||
SELER | SE-lncRNA transcriptional regulation in human malignancies | [211] | |||
TRCirc | Mainly includes transcription of circRNAs and partial SE-circRNAs | [212] |