Fig. 5

Expression and clinical significance of Glut5 in VECs of human colorectal cancer tissue. a, Representative images of IHC staining of Glut5 in colorectal cancer tissues, with red arrows indicating blood vessels and T indicating tumor cells. Scale bar: 50 μm. b, Expression and localization of Glut5 and CD31 in colorectal cancer tissues were detected by IHC staining. Scale bar: 50 μm. c, Representative images of CD31 staining in colorectal cancer tissues. Scale bar: 50 μm. d, Correlation of Glut5 expression in VECs with MVD in colorectal cancer tissues (All case: n = 448; Tumor diameter < 5 cm: n = 224; Tumor diameter ≥ 5 cm: n = 224). e, Correlation of Glut5 expression in VECs with overall survival of colorectal cancer patients (All case: n = 448; Tumor diameter < 5 cm: n = 224; Tumor diameter ≥ 5 cm: n = 224). All data are expressed as the mean ± SD; ns, non-significant; *p < 0.05; **p < 0.01