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Fig. 6 | Journal of Experimental & Clinical Cancer Research

Fig. 6

From: Sertaconazole-repurposed nanoplatform enhances lung cancer therapy via CD44-targeted drug delivery

Fig. 6

The levels of ROS in vivo. (A) Staining of tumor tissue sections harvested from different treated mice with ROS probe DHE (red) (scale bar: 50 μm) and flow cytometry assay (B). (C) IHC stain of 8-OHdG, Nrf-2, SOD1 and HO-1 of tumor tissues; scale bar: 50 μm (n = 5). (D-J) Elisa assay of MDA (D), SOD (E),8-OHDG (F) and IL-6 (G), IL-8 (H), and TNF-α (I) in mice serum (n = 3). 1:Control; 2:STZ; 3:TS NPs; 4:HTS NPs. The error bars represent the means ± SD (***P < 0.001)

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