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Fig. 6 | Journal of Experimental & Clinical Cancer Research

Fig. 6

From: SENP5 promotes homologous recombination-mediated DNA damage repair in colorectal cancer cells through H2AZ deSUMOylation

Fig. 6

H2AZ is a direct deSUMOylation substrate. A-D SENP5 or H2AZ was immunoblotted in protein complex immunoprecipitated with H2AZ or SENP5 antibody in HCT116 cells (A-B) and HT29 cells (C-D), respectively. E-F Interaction of SENP5 and H2AZ were further validated in HEK-293T cells transfected with Flag-tagged SENP5 and HA-tagged H2AZ. G SUMO2/3 were detected upregulated in SENP5 knockdown cells with protein immunoprecipitated with H2AZ antibody

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Journal of Experimental & Clinical Cancer Research

ISSN: 1756-9966

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