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Table 1 circGUCY1A2 expression and clinicopathological features in non-small cell lung cancer (NSCLC) patients

From: Circadian gene ARNTL initiates circGUCY1A2 transcription to suppress non-small cell lung cancer progression via miR-200c-3p/PTEN signaling

Parameter

No. of patients

circGUCY1A2 (High)

circGUCY1A2 (Low)

P value

Gender

   

0.137

    Male

69

21

48

 

    Female

16

8

8

 

Age(year)

   

0.325

    <60

53

16

37

 

    ≥60

32

13

19

 

Smoking history (years)

   

0.134

    <10

29

13

16

 

    ≥10

56

16

40

 

Pathological type

   

0.090

adenocarcinoma

39

17

22

 

squamous carcinoma

46

12

34

 

Tumor size (cm)

   

< 0.001***

    ≤5

45

23

22

 

    >5

40

6

34

 

Differentiation Grade

   

0.455

    Well-moderate

51

19

32

 

    Poor-undifferentiation

34

10

24

 

TNM stage

   

0.043*

    I-II

55

23

32

 

    III-IV

30

6

24

 

Metastasis

   

0.5228

    Yes

22

5

13

 

    No

63

24

43

 
  1. Footnote: The TNM Staging System is based on the tumor (T), the extent of spread to the lymph nodes (N), and the presence of metastasis (M)*P < 0.05, ***P < 0.001