Fig. 2

IL-6 signaling responsiveness in breast cancer patients’ CD4⁺ naïve T cells compared to healthy donors measured by phosphoflow cytometry. Median fluorescent intensity (MFI) of p-STAT1 and p-STAT3 between CD4⁺ naïve T cells stimulated with IL-6 minus unstimulated in healthy donors and breast cancer patients A. Flow-cytometry expression of IL-6Rα and GP130 on CD4⁺ naïve T cells in healthy donors and breast cancer patients, and the correlation with IL-6 signaling responsiveness of p-STAT1 and p-STAT3 B. Modified from Wang et al., Cancer Res. 2017 [19]. Copyright© 2017. American Association for Cancer Research