Fig. 4

CHSY1 induced CD8⁺ T cell exhaustion and upregulated PD-L1 expression. A A total of 33 cell clusters were divided, and we defined the respective group of the mass cytometry results. B TSNE plot showing distribution of 33 cell clusters in the respective sample. C The histogram showing the number of the respective cell clusters in different groups by mass cytometry. D TSNE plot showing distribution of PD1, PD-L1, TIGIT, and CD19 in two groups. E The histogram showing the expression of PD1, PD-L1, TIGIT, and CD19 in different groups