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Fig. 6 | Journal of Experimental & Clinical Cancer Research

Fig. 6

From: CHSY1 promotes CD8+ T cell exhaustion through activation of succinate metabolism pathway leading to colorectal cancer liver metastasis based on CRISPR/Cas9 screening

Fig. 6

Metabonomics analysis of down-regulating CHSY1 in CRC cells. A circos plot showing correlations between multiple differential metabolites. B According to the structure and function of the metabolites, the different metabolites in each control group were classified and counted, and the classification results of the substances in the KEGG and HMDB databases were provided respectively. C Top 20 up-regulated metabolites and top 20 down-regulated metabolites. D, E KEGG pathway analysis indicated the main concentrated pathways of these differential metabolites. F Sankey diagram visualization of data flow trends between down-regulated metabolites and various pathways

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Journal of Experimental & Clinical Cancer Research

ISSN: 1756-9966

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