Fig. 1

sPD1 and sPD-L1 levels in plasma of MM patients underwent immunotherapy with ICI. A Violin plots with median showing sPD1 and sPD-L1 plasma levels (pg/mL) in MM patients (RES and NRES) measured by ELISA assay (*p < 0.05). B Kaplan–Meier survival curve of MM patients with high or low sPD1 and sPD-L1 level as respect to PFS and OS. C Scatter plots with median showing sPD1 and sPD-L1 plasma levels fold change of the first-response/basal and of the second-response/first-response or of the progression/response of NRES, long RES and RES > PRO MM patients