Fig. 2

PDX and PDTO recapitulate the heterogeneity of histologic features and expression of OCCC markers of the original tumor. Comparative histologic, morphologic and IHC images of tumor-derived models (PDX, PDTO and cell lines) compared with the original tumor. Top row, H&E staining of patient tumor, PDTOs and PDX and Giemsa staining of tumor-derived cell lines. Next rows, IHC staining of Ki-67, PAX8, p53, WT1 and HNF1B. Scale bar: 100µm