Fig. 8

Histopathological analysis of bone marrow architecture after IGF2BP1 and ETV6::RUNX1 overexpression A) Quantitation of Lin- c-Kit+ cells and Lin- c-Kit+ Sca1+ cells (LSK population) in different mouse groups B) Ki67 positivity in the lineage negative cells of the bone marrow belonging to different groups C) Histologic imaging of bone marrow of mice belonging to different groups; *fat globules, +megakaryocytes, X: vascular space; Scale bar:100 microns (200X) D) Quantitation of Igf2bp1 and ETV6::RUNX1 expression in mouse bone marrow (t-test; p * <0.05, ** <0.01, *** <0.005, **** <0.0001)