Fig. 1

LMP1 promotes anoikis resistance and invasion of NPC cells. A Cell survival rate of CNE1/CM, HNE2/HM, CM-con/CM-shLMP1, HM-con/HM-shLMP1 cells after 0, 2, 4, or 6 days suspension (**p < 0.01, *p < 0.05). B CNE1/CM, HNE2/HM, CM-con/CM-shLMP1, HM-con/HM-shLMP1 cells were cultured in suspension for 48 h, and the expression of LMP1, cleaved-PARP-1, and cleaved-Caspase 3 was detected by Western blotting. C CNE1/CM, HNE2/HM, CM-con/CM-shLMP1, and HM-con/HM-shLMP1 cells were cultured in suspension for 7 days, and the colony formation rate of the cells reattached was observed (**p < 0.01, *p < 0.05). D CNE1/CM, HNE2/HM, CM-con/CM-shLMP1, and HM-con/HM-shLMP1 cells were cultured in suspension for 48 h, and the apoptotic rate of cells was detected by flow cytometry (**p < 0.01). E CNE1/ CM/CM-shLMP1 and HNE2/HM/HM-shLMP1 cells were cultured in suspension for 48 h, and the apoptotic rate of cells was detected by TUNEL assay, respectively (***p < 0.001,**p < 0.01, *p < 0.05). bar, 200μm. CNE1/CM, HNE2/HM, CM-con/CM-shLMP1, and HM-con/HM-shLMP1 cells were cultured in suspension for 7 days, and (F) the migration and (G) invasion abilities were detected by cell migration assay (**p < 0.01, *p < 0.05)