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Table 1 Univariate and multivariate analyses of prognostic factors in CCA patients

From: Hypoxia-induced SKA3 promoted cholangiocarcinoma progression and chemoresistance by enhancing fatty acid synthesis via the regulation of PAR-dependent HIF-1a deubiquitylation

Variable

Univariate analysis

Multivariate analysis

HR

95% CI

P value

HR

95% CI

P value

Sex

0.643

0.406–1.018

0.060

   

Age

0.804

0.519–1.244

0.327

   

Tumour size (cm)

1.626

0.984–2.689

0.058

   

Differentiation

1.307

0.753–2.269

0.354

   

Perineural invasion

1.279

0.766–2.135

0.355

   

R0 resection

1.249

0.575–2.711

0.574

   

TNM stage

1.378

0.836–2.272

0.209

   

Lymphatic metastasis

2.918

1.765–4.821

 < 0.001*

2.792

1.688–4.619

 < 0.001*

Vascular Invasion

1.361

0.765–2.423

0.294

   

SKA3 Expression

1.795

1.111–2.900

0.017*

1.627

1.003–2.641

0.049*

  1. *P < 0.05