Fig. 4

Mitochondrial gene elevation in circulating tumor cells and bone metastases of poor survival in PCa patients. (A) Significantly up-regulated DE genes in circulating tumor cells from PCa patients were enriched to the mitochondrial structural components. Data were processed from the previously published study [59], and the plot was generated using ShinyGO v0.61. (B) Patients with MT-ND1 gene expression at a low level, compared to patients expressed MT-ND1 at a high level, has a favorable prognostic trend in PCa patients with bone metastases (n = 16 high vs. n = 17 low, p = 0.39, from cBioportal study ID: prad_su2c_2019)