Fig. 7

lnc-MLETA1 is upregulated in tumor tissues and predicts poor survival in lung cancer patients. A-C The expression of lnc-MLETA1 (A), EGFR (B) and IGF1R (C) between non-tumor and tumor tissue in the GSE19188 dataset. The data were analyzed with two-tailed Student’s t-test. D and E The Pearson correlation analysis of the expression of lnc-MLETA1 and EGFR (D) or IGF1R (E) in the GSE19188 dataset. F–H Kaplan–Meier analysis of overall survival in lung adenocarcinoma patients with high or low lnc-MLETA1 (F), EGFR (G) and IGF1R (H) expression. I and J Kaplan–Meier analysis of overall survival in lung adenocarcinoma patients with high- or low-scoring groups using the gene expression of lnc-MLETA1 plus EGFR (I) and lnc-MLETA1 plus IGF1R (J). The patients were divided into high and low groups based on the median expression value of the gene in the cohort and the data were analyzed with log-rank test. K and L ROC curve analysis of plasma exosomal lnc-MLETA1 for lung cancer metastasis (K) and lung cancer (L). Results are presented as mean ± SD. **P < 0.01, ***P < 0.001