Fig. 1

SF3B4 is overexpressed in HCC and clinically correlated with its prognosis. A SF3B4 expression in tumor and non-tumor tissues in the pan-cancer database of TCGA. B Kaplan–Meier survival analyses of SF3B4 expression in TCGA_LIHC datasets for OS, DFS, DSS, and PFS. C Forest plot of univariate Cox regression analyses of clinical parameters for OS (left) and DFS (right) (***P <0.001). D Representative images of SF3B4 expression in HCC tissues and the proportion of patients with different SF3B4 immunostaining levels in liver cancer specimens based on HPA data. Scale bar = 100 µm. E. Representative IHC photomicrographs of SF3B4 in HCC (T, tumor tissues; NT, non-tumor tissues). Scale bar = 300 µm