Table 1 Immune cells related markers and correlation with SF3B4
Description | Markers | SF3B4 (LIHC, 371) | |
|---|---|---|---|
Corr | P value | ||
T cell (general) | CD3D | 0.198 | 1.24e-04 |
CD3E | 0.11 | 3.99e-02 | |
CD3G | 0.096 | 6.38e-02 | |
CD2 | 0.125 | 1.58e-02 | |
Cytotoxic T cell | CD8A | 0.08 | 1.23e-01 |
CD8B | 0.088 | 8.97e-02 | |
Helper T cell | CD4 | -0.021 | 6.92e-01 |
Follicular Helper T (Tfh) cells | CXCR5 | 0.158 | 2.33e-03 |
ICOS | 0.206 | 6.54e-05 | |
PD-1 (PDCD1) | 0.256 | 5.7e-07 | |
IL21 | 0.014 | 7.92e-01 | |
CXCL13 | 0.119 | 2.14e-02 | |
BCL6 | 0.208 | 5.72e-05 | |
T helper type 1 (Th1) | CCR5 | 0.136 | 8.71e-03 |
CXCR3 | 0.185 | 3.41e-04 | |
IFG-gamma (IFNG) | 0.173 | 7.97e-04 | |
T-bet (TBX21) | -0.021 | 6.9e-01 | |
STAT4 | 0.155 | 2.84e-03 | |
STAT1 | 0.266 | 2.1e-07 | |
T helper type 2 (Th2) | GATA3 | 0.091 | 8.03e-02 |
STAT6 | 0.195 | 1.6e-04 | |
IL13 | 0.059 | 2.61e-01 | |
T helper type 17 (Th17) | STAT3 | 0.129 | 1.28e-02 |
IL17A | 0.061 | 2.38e-01 | |
Regulatory T cell (Treg) | IL2RA | 0.186 | 3.23e-04 |
ENTPD1 | 0.271 | 1.26e-07 | |
FoxP3 | 0.046 | 3.78e-01 | |
CCR8 | 0.231 | 6.89e-06 | |
T cell exhaustion | CTLA4 | 0.253 | 7.66e-07 |
LAG3 | 0.177 | 6.07e-04 | |
TIM-3 (HAVCR2) | 0.187 | 2.92e-04 | |
Natural Killer (NK) cell | CD56 (NCAM1) | 0.149 | 4.1e-03 |
KLRD1 | -0.116 | 2.51e-02 | |
NKG2A (KLRC1) | 0.039 | 4.59e-01 | |
NKG2D (KLRK1) | -0.026 | 6.12e-01 | |
NCR1 (NKp46) | -0.071 | 1.71e-01 | |
NCR2 (NKp44) | 0.081 | 1.21e-01 | |
NCR3 (NKp30) | 0.02 | 6.98e-01 | |
Pan Macrophage marker | CD68 | 0.127 | 1.42e-02 |
M1 macrophage | IL1B | 0.273 | 9.62e-08 |
IL6 | -0.025 | 6.36e-01 | |
IL12A | 0.355 | 1.9e-12 | |
IL12B | 0.047 | 3.72e-01 | |
IL23A | 0.14 | 6.73e-03 | |
TNF-alpha (TNF) | 0.184 | 3.62e-04 | |
INOS (NOS2) | 0.032 | 5.43e-01 | |
IRF5 | 0.462 | 5.67e-21 | |
COX2 (PTGS2) | 0.077 | 1.37e-01 | |
M2 macrophage | CD163 | -0.045 | 3.88e-01 |
PPARδ | 0.448 | 1.11e-19 | |
PPARγ | 0.262 | 2.98e-07 | |
MRC1 (CD206) | -0.167 | 1.25e-03 | |
CD209 | 0.078 | 1.34e-01 | |
IRF4 | 0.121 | 1.99e-02 | |
STAT3 | 0.129 | 1.27e-02 | |
CCL17 | 0.1 | 5.43e-02 | |
Myeloid-Derived Suppressor Cells (MDSC) | HLA-DRA | 0.125 | 1.64e-02 |
HLA-DRB1 | 0.083 | 1.09e-01 | |
CD33 | 0.11 | 3.46e-02 | |
CD11b (ITGAM) | 0.285 | 2.65e-08 | |
CD14 (negative) | -0.296 | 6.28e-09 | |
IDO(IDO1) | 0.068 | 1.89e-01 | |
LOX | 0.208 | 5.46e-05 | |
S100A8 | 0.102 | 5.03e-02 | |
S100A9 | 0.26 | 3.82e-07 | |
CD80 | 0.236 | 4.12e-06 | |
CD83 | 0.349 | 4.39e-12 | |
B cell | CD45 (PTPRC) | 0.101 | 5.14e-02 |
CD19 | 0.217 | 2.56e-05 | |
CD79A | 0.116 | 2.5e-02 | |
Neutrophils | CD66b (CEACAM8) | -0.024 | 6.51e-01 |
CXCR1 | 0.054 | 3e-01 | |
CXCR2 | 0.136 | 8.74e-03 | |
MPO | -0.003 | 9.58e-01 | |
Dendritic cells | IL3RA (CD123) | 0.073 | 1.59e-01 |
ITGAX (CD11c) | 0.204 | 7.81e-05 | |
CD1c (BDCA1) | 0.094 | 7.13e-02 | |
CLEC4C (BDCA2) | 0.053 | 3.13e-01 | |