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Fig. 8 | Journal of Experimental & Clinical Cancer Research

Fig. 8

From: Tumor-associated macrophage-derived exosomes LINC01592 induce the immune escape of esophageal cancer by decreasing MHC-I surface expression

Fig. 8

Correlation of LINC01592/E2F6/NBR1/MHC-I axis with clinical progression. A-D. Expression levels of LINC01592/E2F6/NBR1/MHC-I in NEE and different grades of esophageal cancer by qRT-PCR. E. Spearman correlation analysis between LINC01592 levels and E2F6 levels in tumor tissues from esophageal cancer patients. Pearson's correlation coefficient (r) and P-value, as the picture showed, n = 118. The P-value was from Spearman's test. F. Spearman correlation analysis between LINC01592 levels and NBR1 levels in tumor tissues from esophageal cancer patients. Pearson's correlation coefficient (r) and P-value, as the picture showed, n = 118. The P-value was from Spearman's test. G. Spearman correlation analysis between LINC01592 levels and MHC-I levels in tumor tissues from esophageal cancer patients. Pearson's correlation coefficient (r) and P-value, as the picture showed, n = 118. The P-value was from Spearman's test. H. Spearman correlation analysis between E2F6 levels and MHC-I levels in tumor tissues from esophageal cancer patients. Pearson's correlation coefficient (r) and P-value, as the picture showed, n = 118. The P-value was from Spearman's test. I. Spearman correlation analysis between NBR1 levels and MHC-I levels in tumor tissues from esophageal cancer patients. Pearson's correlation coefficient (r) and P-value, as the picture showed, n = 118. The P-value was from Spearman's test. J. Spearman correlation analysis between Linc01060 expression levels and E2F6, NBR1, and MHC-I expression levels in esophageal cancer tissues. Pearson's correlation coefficient (r) and P-value, as the picture showed; the P-value was from Spearman's test. The scale bar represents 50 μm. The means ± SDs are provided (n = 3). *P < 0.05, **P < 0.01, and ***P < 0.001 according to two-tailed Student t-tests or one-way ANOVA followed by Dunnett tests for multiple comparisons. ns, no significant difference

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