Fig. 4From: Targeting of RRM2 suppresses DNA damage response and activates apoptosis in atypical teratoid rhabdoid tumorCOH29 suppressed tumor growth and prolonged survival of ATRT mice in vivo. A In vivo experimental schema. B Brain MRI images of mice in the control group and COH29-treated group in pre- and post-treatment. C Representative of the change in tumor volume between the COH29-treated group and control group. *p < 0.05, Unpaired t-test. The data are presented as the median ± interquartile range. D The overall survival of ATRT mice in control group and COH29-treated group. **p < 0.01, Log-rank (Mantel-Cox) testBack to article page