Fig. 7
PET imaging of 64Cu-radiolabeled αFAP-scFv TM and -IgG4 TM in tumor xenograft mouse model. After radiolabeling with 64Cu, both αFAP TMs were injected intravenously in NMRI nude mice bearing HT1080 (left flank, highlighted by red circles) and HT1080 hFAP (right flank, highlighted by green circles) tumors. PET/CT imaging was performed up to 48 h post-injection (p.i.) and standardized uptake values (SUV) were calculated for the αFAP-scFv TM (a, b) and αFAP-IgG4 TM (c, d) at the different time points